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Preferred Term:

proteasome endopeptidase complex

Definition:
A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.
Concept Schemes:
NALT Full
https://lod.nal.usda.gov/nalt-core
Broader Concept:
Entry Terms:
  • proteasome complex
  • EC 3.4.25.1
  • proteasome
URI:
https://lod.nal.usda.gov/nalt/126796
Download this Concept:
RDF/XMLCreated 2008-10-24, last modified 2017-05-02
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