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NALT Concept Space
U.S. Department of Agriculture

NALT Core

Concept information

  1. Fields of Study
  2. biochemistry
  3. biochemical compounds
  4. amino acids, peptides and proteins
  5. proteins
  6. prions
  1. Research, Technology, Methods
  2. chemical substances
  3. biochemical compounds
  4. amino acids, peptides and proteins
  5. proteins
  6. prions

Preferred term

prions

Type

  • Chemical

Definition

  • Information Small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc; the cellular isoform is PrPC. The primary amino acid sequence of the two isoforms is identical. Among diseases caused by prions are scrapie, bovine spongiform encephalopathy, and Creuzfeldt-Jakob Syndrome.

    Source: Medical Subject Headings

    Type: Concept definition

Broader concept

Narrower concepts

Related concepts

Synonyms

  • prion proteins
  • PrP proteins

In other languages

URI

https://lod.nal.usda.gov/nalt/40965

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RDF/XML TURTLE JSON-LD Created 1/19/06, last modified 12/30/15