Preferred Term:
buprenorphine
Definition:
A derivative of the opioid alkaloid thebaine that is a more potent and longer lasting analgesic than morphine. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Concept Schemes:
NALT Full
Broader Concept:
Entry Terms:
- buprenorphine hydrochloride
URI:
https://lod.nal.usda.gov/nalt/8452
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RDF/XMLCreated 2006-01-19, last modified 2016-06-30
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