Concept information
Preferred term
buprenorphine
Type
-
Chemical
Definition
-
A derivative of the opioid alkaloid thebaine that is a more potent and longer lasting analgesic than morphine. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Source: Medical Subject Headings 2012
Type: Concept definition
Broader concept
Synonyms
- buprenorphine hydrochloride
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/8452
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