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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. genetics
  3. molecular genetics
  4. protein synthesis
  5. post-translational modification
  6. unfolded protein response
  1. Fields of Study
  2. metabolism
  3. protein metabolism
  4. protein synthesis
  5. post-translational modification
  6. unfolded protein response
  1. Fields of Study
  2. metabolism
  3. protein metabolism
  4. protein synthesis
  5. post-translational modification
  6. unfolded protein response

Preferred term

unfolded protein response

Type

  • Topic

Definition

  • Information A cellular response to environmental insults that cause disruptions in protein folding and/or accumulation of defectively folded protein in the endoplasmic reticulum. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of apoptosis.

    Source: Medical Subject Headings

    Type: Concept definition

Broader concept

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URI

https://lod.nal.usda.gov/nalt/146596

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RDF/XML TURTLE JSON-LD Created 8/1/11, last modified 5/1/17