Concept information
- Animals, Livestock, One Health
- animal and human health
- diseases and disorders (animals and humans)
- skin diseases
Preferred term
dermatomyositis
Type
-
Topic
Definition
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A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms.
Source: Medical Subject Headings
Type: Concept definition
Broader concept
In other languages
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Spanish
URI
https://lod.nal.usda.gov/nalt/154505
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