Concept information
Preferred term
autophagy
Type
-
Topic
Definition
-
The segregation and degradation of various cytoplasmic constituents via engulfment by multivesicular bodies; vacuoles; or autophagosomes and their digestion by lysosomes. It plays an important role in biological metamorphosis and in the removal of bone by osteoclasts. Defective autophagy is associated with various diseases, including neurodegenerative diseases and cancer.
Source: Medical Subject Headings
Type: Concept definition
Broader concept
Narrower concepts
Synonyms
- autophagic cell death
- autophagic programmed cell death
- autophagocytosis
- type 2 programmed cell death
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/206099
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