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Concept information

Preferred term

tumor suppressor genes

Type

  • Topic

Definition

  • Information Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.

Broader concept

Synonyms

  • anti-oncogenes
  • antioncogenes
  • cancer suppressor genes
  • metastasis suppressor genes
  • tumor suppressing genes
  • tumour suppressing genes
  • tumour suppressor genes

In other languages

URI

https://lod.nal.usda.gov/nalt/207970

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