Concept information
Preferred term
tumor suppressor genes
Type
-
Topic
Definition
-
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
Source: Medical Subject Headings 2014
Type: Concept definition
Broader concept
Synonyms
- anti-oncogenes
- antioncogenes
- cancer suppressor genes
- metastasis suppressor genes
- tumor suppressing genes
- tumour suppressing genes
- tumour suppressor genes
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/207970
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