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Concept information

  1. Fields of Study
  2. mathematics and statistics
  3. analytical methods
  4. spectroscopy
  5. mass spectrometry
  6. matrix-assisted laser desorption-ionization mass spectrometry
  1. Research, Technology, Methods
  2. mathematics and statistics
  3. analytical methods
  4. spectroscopy
  5. mass spectrometry
  6. matrix-assisted laser desorption-ionization mass spectrometry
  1. Research, Technology, Methods
  2. mathematics and statistics
  3. analytical methods
  4. spectroscopy
  5. mass spectrometry
  6. matrix-assisted laser desorption-ionization mass spectrometry

Preferred term

matrix-assisted laser desorption-ionization mass spectrometry

Type

  • Topic

Definition

  • Information A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions.

Broader concept

Synonyms

  • MALDI mass spectrometry
  • MALDI-MS (mass spectrometry)
  • MALDI-TOF mass spectrometry
  • MALDI-TOF-MS (mass spectrometry)
  • matrix-assisted laser desorption-ionization time-of-flight mass spectrometry
  • SELDI mass spectrometry
  • SELDI-MS (mass spectrometry)
  • surface enhanced laser desorption ionization mass spectrometry

URI

https://lod.nal.usda.gov/nalt/207987

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