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Concept information

Preferred term

vascular endothelial growth factor receptors

Type

  • Chemical

Definition

  • Information A family of closely related receptor protein-tyrosine kinases that bind vascular endothelial growth factors. They share a cluster of seven extracellular Ig-like domains which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.

Synonyms

  • endothelial growth factor receptor
  • vascular endothelial cell growth factor receptor
  • vascular permeability factor receptor
  • VEGF receptor
  • VEGF receptors
  • VPF receptor

URI

https://lod.nal.usda.gov/nalt/208102

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RDF/XML TURTLE JSON-LD Created 11/15/13, last modified 12/6/13