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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. protein kinases
  3. protein-tyrosine kinases
  4. receptor protein-tyrosine kinase
  5. vascular endothelial growth factor receptors
  6. vascular endothelial growth factor receptor-1
  1. Research, Technology, Methods
  2. protein kinases
  3. protein-tyrosine kinases
  4. receptor protein-tyrosine kinase
  5. vascular endothelial growth factor receptors
  6. vascular endothelial growth factor receptor-1

Preferred term

vascular endothelial growth factor receptor-1

Type

  • Chemical

Definition

  • Information A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.

    Source: Medical Subject Headings 2014

    Type: Concept definition

Broader concept

Synonyms

  • flt1 receptor tyrosine kinase
  • proto-oncogene protein flt
  • VEGFR-1
  • VEGF receptor flt
  • VEGF receptor flt-1 protein

In other languages

URI

https://lod.nal.usda.gov/nalt/208111

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RDF/XML TURTLE JSON-LD Created 11/15/13, last modified 4/21/15