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Concept information

Preferred term

angiopoietin-2

Type

  • Chemical

Definition

  • Information An angiopoietin that is closely related to angiopoietin-1. It binds to the TIE-2 receptor without receptor stimulation and antagonizes the effect of angiopoietin-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of blood vessel branching and sprouting.

Broader concept

In other languages

URI

https://lod.nal.usda.gov/nalt/215208

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RDF/XML TURTLE JSON-LD Created 4/22/14, last modified 11/17/14