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Concept information

Preferred term

antibody affinity

Type

  • Topic

Definition

  • Information A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.

Broader concept

Synonyms

  • antibody avidity

In other languages

URI

https://lod.nal.usda.gov/nalt/217636

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