Concept information
Preferred term
antibody affinity
Type
-
Topic
Definition
-
A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
Source: Medical Subject Headings 2014
Type: Concept definition
Broader concept
Synonyms
- antibody avidity
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/217636
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