Concept information
Preferred term
neoplasm proteins
Type
-
Chemical
Definition
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Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of neoplasms. Some neoplasm proteins are tumor antigens (antigens, neoplasm), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (tumor markers, biological) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of oncogene proteins is involved in neoplastic transformation, whereas the loss of expression of tumor suppressor proteins is involved with the loss of growth control and progression of the neoplasm.
Source: Medical Subject Headings 2014
Type: Concept definition
Broader concept
Narrower concepts
In other languages
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Spanish
URI
https://lod.nal.usda.gov/nalt/217644
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