Concept information
Preferred term
PrPC proteins
Type
-
Chemical
Definition
-
Normal cellular isoform of prion proteins (prions) encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.
Source: Medical Subject Headings 2014
Type: Concept definition
Broader concept
In other languages
URI
https://lod.nal.usda.gov/nalt/217658
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