Concept information
Preferred term
cholinesterase inhibitors
Type
-
Chemical
Definition
-
Drugs that inhibit cholinesterases. The neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Source: Medical Subject Headings
Type: Concept definition
Broader concept
Synonyms
- acetylcholinesterase inhibitors
- anticholinesterase agents
- anticholinesterase drugs
- anti-cholinesterases
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/22191
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