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Concept information

Preferred term

cholinesterase inhibitors

Type

  • Chemical

Definition

  • Information Drugs that inhibit cholinesterases. The neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.

Broader concept

Synonyms

  • acetylcholinesterase inhibitors
  • anticholinesterase agents
  • anticholinesterase drugs
  • anti-cholinesterases

In other languages

URI

https://lod.nal.usda.gov/nalt/22191

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RDF/XML TURTLE JSON-LD Created 1/19/06, last modified 12/16/19