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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. phosphotransferases (kinases)
  3. protein kinases
  4. protein-tyrosine kinases
  5. receptor protein-tyrosine kinase
  6. epidermal growth factor receptors
  1. Research, Technology, Methods
  2. phosphotransferases (kinases)
  3. protein kinases
  4. protein-tyrosine kinases
  5. receptor protein-tyrosine kinase
  6. epidermal growth factor receptors
  1. Fields of Study
  2. proteins
  3. receptors
  4. hormone receptors
  5. gastrointestinal hormone receptors
  6. epidermal growth factor receptors
  1. Research, Technology, Methods
  2. proteins
  3. receptors
  4. hormone receptors
  5. gastrointestinal hormone receptors
  6. epidermal growth factor receptors
  1. Fields of Study
  2. amino acids, peptides and proteins
  3. proteins
  4. membrane proteins
  5. peptide receptors
  6. epidermal growth factor receptors
  1. Research, Technology, Methods
  2. amino acids, peptides and proteins
  3. proteins
  4. membrane proteins
  5. peptide receptors
  6. epidermal growth factor receptors
  1. Fields of Study
  2. amino acids, peptides and proteins
  3. proteins
  4. receptors
  5. peptide receptors
  6. epidermal growth factor receptors
  1. Research, Technology, Methods
  2. amino acids, peptides and proteins
  3. proteins
  4. receptors
  5. peptide receptors
  6. epidermal growth factor receptors

Preferred term

epidermal growth factor receptors

Type

  • Chemical

Definition

  • Information A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for epidermal growth factor and EGF related peptides including transforming growth factor alpha, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.

    Source: Medical Subject Headings 2014

    Type: Concept definition

Broader concept

Related concepts

Synonyms

  • c-erbB-1 protein
  • EGF receptor
  • EGFR protein
  • epidermal growth factor receptor kinase
  • epidermal growth factor receptor protein-tyrosine kinase
  • epidermal growth factor-urogastrone receptor
  • erbB-1 proto-oncogene protein
  • TGF-alpha receptor
  • transforming growth factor alpha receptor
  • transforming growth factor-alpha receptor
  • transforming-growth factor alpha receptor
  • urogastrone receptor

In other languages

URI

https://lod.nal.usda.gov/nalt/222853

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RDF/XML TURTLE JSON-LD Created 7/25/14, last modified 11/17/14