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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. phosphotransferases (kinases)
  3. protein kinases
  4. protein-tyrosine kinases
  5. receptor protein-tyrosine kinase
  6. hepatocyte growth factor receptor
  1. Research, Technology, Methods
  2. phosphotransferases (kinases)
  3. protein kinases
  4. protein-tyrosine kinases
  5. receptor protein-tyrosine kinase
  6. hepatocyte growth factor receptor

Preferred term

hepatocyte growth factor receptor

Type

  • Chemical

Definition

  • Information Cell surface protein-tyrosine kinase receptors for hepatocyte growth factor. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations of the gene for proto-oncogene proteins c-Met are associated with papillary renal carcinoma and other neoplasia.

    Source: Medical Subject Headings 2014

    Type: Concept definition

Broader concept

Synonyms

  • c-Met proteins
  • c-Met proto-oncogene proteins
  • HGF receptor
  • HGF/SF receptor
  • Met proto-oncogene tyrosine kinase
  • proto-oncogene c-Met
  • proto-oncogene protein c-Met
  • proto-oncogene proteins c-Met
  • receptor tyrosine kinase c-Met
  • scatter factor receptor
  • SF receptor
  • tyrosine-protein kinase Met

In other languages

URI

https://lod.nal.usda.gov/nalt/222854

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RDF/XML TURTLE JSON-LD Created 7/25/14, last modified 5/25/18