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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. phosphotransferases (kinases)
  3. protein kinases
  4. protein-tyrosine kinases
  5. receptor protein-tyrosine kinase
  6. insulin receptors
  1. Research, Technology, Methods
  2. phosphotransferases (kinases)
  3. protein kinases
  4. protein-tyrosine kinases
  5. receptor protein-tyrosine kinase
  6. insulin receptors
  1. Fields of Study
  2. proteins
  3. receptors
  4. hormone receptors
  5. pancreatic hormone receptors
  6. insulin receptors
  1. Research, Technology, Methods
  2. proteins
  3. receptors
  4. hormone receptors
  5. pancreatic hormone receptors
  6. insulin receptors

Preferred term

insulin receptors

Type

  • Chemical

Definition

  • Information A cell surface receptor for insulin. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic tyrosine kinase domain that is located within the beta subunit. Activation of the receptor by insulin results in numerous metabolic changes including increased uptake of glucose into the liver, muscle, and adipose tissue.

    Source: Medical Subject Headings 2014

    Type: Concept definition

Broader concept

Narrower concepts

Related concepts

Synonyms

  • insulin-dependent tyrosine protein kinase
  • insulin receptor alpha chain
  • insulin receptor alpha subunit
  • insulin receptor beta chain
  • insulin receptor beta subunit
  • insulin receptor protein-tyrosine kinase

In other languages

URI

https://lod.nal.usda.gov/nalt/222855

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RDF/XML TURTLE JSON-LD Created 7/25/14, last modified 3/2/17