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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. phosphotransferases (kinases)
  3. protein kinases
  4. protein-tyrosine kinases
  5. receptor protein-tyrosine kinase
  6. erbB-3 receptor
  1. Research, Technology, Methods
  2. phosphotransferases (kinases)
  3. protein kinases
  4. protein-tyrosine kinases
  5. receptor protein-tyrosine kinase
  6. erbB-3 receptor

Preferred term

erbB-3 receptor

Type

  • Chemical

Definition

  • Information A cell surface protein-tyrosine kinase receptor that is specific for neuregulins. It has extensive homology to and can heterodimerize with the EGF Receptor (epidermal growth factor receptor) and the erbB-2 receptor. Overexpression of the erbB-3 receptor is associated with tumorigenesis.

    Source: Medical Subject Headings 2014

    Type: Concept definition

Broader concept

Synonyms

  • c-erbB-3 protein
  • c-erbB-3 receptor
  • HER-3 protein
  • HER-3 proto-oncogene protein
  • HER-3 receptor
  • human epidermal growth factor receptor 3
  • proto-oncogene protein c-erbB-3
  • proto-oncogene proteins erbB-3

In other languages

URI

https://lod.nal.usda.gov/nalt/222857

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RDF/XML TURTLE JSON-LD Created 7/25/14, last modified 11/17/14