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Concept information

Preferred term

angiotensin-converting enzyme inhibitors

Type

  • Chemical

Definition

  • Information A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.

Broader concept

Synonyms

  • ACE inhibitors
  • angiotensin I-converting enzyme inhibitors
  • kininase II antagonists
  • kininase II inhibitors

URI

https://lod.nal.usda.gov/nalt/228984

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RDF/XML TURTLE JSON-LD Created 9/17/14, last modified 4/14/20