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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. genetics
  3. molecular genetics
  4. proliferating cell nuclear antigen
  1. Fields of Study
  2. immunology
  3. immunologic factors
  4. antigens
  5. nuclear antigens
  6. proliferating cell nuclear antigen
  1. Fields of Study
  2. amino acids, peptides and proteins
  3. proteins
  4. nuclear proteins
  5. nuclear antigens
  6. proliferating cell nuclear antigen
  1. Research, Technology, Methods
  2. amino acids, peptides and proteins
  3. proteins
  4. nuclear proteins
  5. nuclear antigens
  6. proliferating cell nuclear antigen

Preferred term

proliferating cell nuclear antigen

Type

  • Chemical

Definition

  • Information Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.

    Source: Medical Subject Headings 2012

    Type: Concept definition

Broader concept

Related concepts

Synonyms

  • PCNA (proliferating cell nuclear antigen)

In other languages

URI

https://lod.nal.usda.gov/nalt/23384

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RDF/XML TURTLE JSON-LD Created 1/19/06, last modified 7/6/17