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Concept information

Preferred term

CCR8 receptor

Type

  • Chemical

Definition

  • Information This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues.

Broader concept

Synonyms

  • CC chemokine receptor 8
  • C-C chemokine receptor type 8
  • CC-CKR8 receptor
  • CDw198 antigen
  • chemokine (C-C motif) receptor 8
  • chemokine (C-C) receptor 8
  • chemokine receptor CKRL1
  • chemokine receptor CLR-L1
  • chemokine receptor TER1
  • CKR8 receptor
  • GPR-CY6 (G-protein coupled receptor-CY6)

In other languages

URI

https://lod.nal.usda.gov/nalt/243493

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