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Concept information

Preferred term

CXCR4 receptor

Type

  • Chemical

Definition

  • Information CXCR4 shares features common to G protein coupled receptors. CXCR4 is a receptor for the CXC chemokine PBSF/SDF1 and functions as a co-receptor for HIV-1. CXCR4 is broadly expressed in the immune and the central nervous systems and can mediate migration of resting leukocytes and hematopoietic progenitors in response to SDF1. PBSF/SDF1 and CXCR4 define a signaling system for organ vascularization.

Broader concept

Synonyms

  • CD184 antigen
  • chemokine (C-X-C motif) receptor 4
  • chemokine (C-X-C) receptor 4
  • CXC chemokine receptor 4
  • C-X-C chemokine receptor type 4
  • fusin
  • LAP-3 protein
  • LESTR (leukocyte-derived seven transmembrane domain receptor)
  • LESTR receptor
  • lipopolysaccharide-associated protein 3
  • LPS-associated protein 3
  • neuropeptide Y receptor Y3
  • PSSF receptor (pre-B cell growth-stimulating factor receptor)
  • SDF1-PBSF receptor
  • SDF-1 receptor
  • SDF-1 (stromal cell-derived factor 1 receptor)
  • seven-transmembrane-segment receptor, spleen

In other languages

URI

https://lod.nal.usda.gov/nalt/243588

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RDF/XML TURTLE JSON-LD Created 3/10/15, last modified 11/16/15