Skip to main content
An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. proteins
  3. membrane proteins
  4. G-protein coupled receptors
  5. chemokine receptors
  6. CXCR4 receptor
  1. Research, Technology, Methods
  2. proteins
  3. membrane proteins
  4. G-protein coupled receptors
  5. chemokine receptors
  6. CXCR4 receptor
  1. Fields of Study
  2. proteins
  3. receptors
  4. G-protein coupled receptors
  5. chemokine receptors
  6. CXCR4 receptor
  1. Research, Technology, Methods
  2. proteins
  3. receptors
  4. G-protein coupled receptors
  5. chemokine receptors
  6. CXCR4 receptor
  1. Fields of Study
  2. membrane proteins
  3. immunologic receptors
  4. cytokine receptors
  5. chemokine receptors
  6. CXCR4 receptor
  1. Research, Technology, Methods
  2. membrane proteins
  3. immunologic receptors
  4. cytokine receptors
  5. chemokine receptors
  6. CXCR4 receptor
  1. Fields of Study
  2. receptors
  3. immunologic receptors
  4. cytokine receptors
  5. chemokine receptors
  6. CXCR4 receptor
  1. Research, Technology, Methods
  2. receptors
  3. immunologic receptors
  4. cytokine receptors
  5. chemokine receptors
  6. CXCR4 receptor

Preferred term

CXCR4 receptor

Type

  • Chemical

Definition

  • Information CXCR4 shares features common to G protein coupled receptors. CXCR4 is a receptor for the CXC chemokine PBSF/SDF1 and functions as a co-receptor for HIV-1. CXCR4 is broadly expressed in the immune and the central nervous systems and can mediate migration of resting leukocytes and hematopoietic progenitors in response to SDF1. PBSF/SDF1 and CXCR4 define a signaling system for organ vascularization.

    Source: National Cancer Institute Thesaurus

    Type: Concept definition

Broader concept

Related concepts

Synonyms

  • CD184 antigen
  • chemokine (C-X-C motif) receptor 4
  • chemokine (C-X-C) receptor 4
  • CXC chemokine receptor 4
  • C-X-C chemokine receptor type 4
  • fusin
  • LAP-3 protein
  • LESTR (leukocyte-derived seven transmembrane domain receptor)
  • LESTR receptor
  • lipopolysaccharide-associated protein 3
  • LPS-associated protein 3
  • neuropeptide Y receptor Y3
  • PSSF receptor (pre-B cell growth-stimulating factor receptor)
  • SDF1-PBSF receptor
  • SDF-1 receptor
  • SDF-1 (stromal cell-derived factor 1 receptor)
  • seven-transmembrane-segment receptor, spleen

In other languages

URI

https://lod.nal.usda.gov/nalt/243588

Download this concept:

RDF/XML TURTLE JSON-LD Created 3/10/15, last modified 11/16/15