Concept information
- Research, Technology, Methods
- proteins
- membrane proteins
- G-protein coupled receptors
- chemokine receptors
Preferred term
CXCR5 receptor
Type
-
Chemical
Definition
-
This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein-coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse counterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.
Source: National Cancer Institute Thesaurus
Type: Concept definition
Broader concept
Synonyms
- BLR-1 receptor
- Burkitt lymphoma receptor 1
- CD185 antigen
- chemokine (C-X-C motif) receptor 5
- chemokine (C-X-C) receptor 5
- CXC chemokine receptor 5
- C-X-C chemokine receptor type 5
- MDR15 receptor
In other languages
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Spanish
URI
https://lod.nal.usda.gov/nalt/243614
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