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Concept information

Preferred term

CXCR5 receptor

Type

  • Chemical

Definition

  • Information This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein-coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse counterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.

Broader concept

Synonyms

  • BLR-1 receptor
  • Burkitt lymphoma receptor 1
  • CD185 antigen
  • chemokine (C-X-C motif) receptor 5
  • chemokine (C-X-C) receptor 5
  • CXC chemokine receptor 5
  • C-X-C chemokine receptor type 5
  • MDR15 receptor

In other languages

URI

https://lod.nal.usda.gov/nalt/243614

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RDF/XML TURTLE JSON-LD Created 3/10/15, last modified 11/16/15