Concept information
Preferred term
platelet-derived growth factor receptors
Type
-
Chemical
Definition
-
Specific receptors on cell membranes that react with platelet-derived growth factor, its analogs, or antagonists. The alpha PDGF receptor (receptor, platelet-derived growth factor alpha) and the beta PDGF receptor (receptor, platelet-derived growth factor beta) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
Source: Medical Subject Headings 2015
Type: Concept definition
Broader concept
Narrower concepts
Synonyms
- PDGF receptors
In other languages
URI
https://lod.nal.usda.gov/nalt/245644
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