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Concept information

Preferred term

thymine-DNA glycosylase

Type

  • Chemical

Definition

  • Information An enzyme that removes thymine and uracil bases mispaired with guanine through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic deamination of 5-methylcytosine to thymine.

Broader concept

Synonyms

  • EC 3.2.2.29
  • G/T glycosylase
  • G:T mismatch-specific thymine DNA-glycosylase
  • mismatch-specific thymine-DNA glycosylase
  • mismatch-specific thymine-DNA N-glycosylase
  • T:G mismatch-specific thymidine-DNA glycosylase
  • thymine-DNA deoxyribohydrolase (thymine-releasing)
  • thymine DNA glycosylase
  • thymine-DNA N-glycosylase
  • uracil/thymine DNA glycosylase

In other languages

URI

https://lod.nal.usda.gov/nalt/247880

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RDF/XML TURTLE JSON-LD Created 4/8/15, last modified 9/28/20