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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. animal and human health
  3. medical sciences
  4. toxicology
  5. toxicity testing
  6. human cell line activation test (h-CLAT)
  1. Animals, Livestock, One Health
  2. animal and human health
  3. medical sciences
  4. toxicology
  5. toxicity testing
  6. human cell line activation test (h-CLAT)
  1. Fields of Study
  2. animal science
  3. medical sciences
  4. toxicology
  5. toxicity testing
  6. human cell line activation test (h-CLAT)
  1. Animals, Livestock, One Health
  2. animal science
  3. medical sciences
  4. toxicology
  5. toxicity testing
  6. human cell line activation test (h-CLAT)
  1. Research, Technology, Methods
  2. research
  3. animal research
  4. toxicology
  5. toxicity testing
  6. human cell line activation test (h-CLAT)
  1. Research, Technology, Methods
  2. methodology
  3. testing
  4. toxicity testing
  5. human cell line activation test (h-CLAT)

Preferred term

human cell line activation test (h-CLAT)

Definition

  • Information The human Cell Line Activation Test is a cell-based assay that identifies if a substance is a skin sensitizing agent without the need for animal testing. The skin sensitizers are identified by examining changes in the expression of cell surface markers (e.g.,CD54 and CD86) implicated in dendritic cell activation.

    Source: AWIC

    Type: Concept definition

Broader concept

In other languages

URI

https://lod.nal.usda.gov/nalt/25325488

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RDF/XML TURTLE JSON-LD Created 4/3/23, last modified 5/4/24