Concept information
Preferred term
tumor suppressor protein p53
Type
-
Chemical
Definition
-
Nuclear phosphoprotein encoded by the p53 gene ( genes, P53) whose normal function is to control cell proliferation and apoptosis. A mutant or absent p53 protein has been found in leukemia; osteosarcoma; lung cancer; and colorectal cancer.
Source: Medical Subject Headings 2015
Type: Concept definition
Broader concept
Synonyms
- oncoprotein p53
- p53 antigen
- TRP53 protein
In other languages
URI
https://lod.nal.usda.gov/nalt/261837
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