Concept information
Preferred term
death domain receptors
Type
-
Chemical
Definition
-
A family of cell surface receptors that signal via a conserved domain that extends into the cell cytoplasm. The conserved domain is referred to as a death domain due to the fact that many of these receptors are involved in signaling apoptosis. Several death domain receptor signaling adaptor proteins can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as caspases.
Source: Medical Subject Headings 2015
Type: Concept definition
Broader concept
Synonyms
- death receptors
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/264095
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