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Concept information

Preferred term

two hybrid system techniques

Type

  • Topic

Definition

  • Information Screening techniques first developed in yeast to identify genes encoding interacting proteins. Variations are used to evaluate interplay between proteins and other molecules. Two-hybrid techniques refer to analysis for protein-protein interactions, one-hybrid for DNA-protein interactions, three-hybrid interactions for RNA-protein interactions or ligand-based interactions.

Broader concept

Synonyms

  • two hybrid analysis
  • two hybrid assay
  • two hybrid screening
  • two-hybrid system
  • yeast-two hybrid assay

In other languages

URI

https://lod.nal.usda.gov/nalt/26951

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