Concept information
- Fields of Study
- amino acids, peptides and proteins
- proteins
- membrane proteins
- G-protein coupled receptors
Preferred term
gamma-aminobutyric acid receptors
Type
-
Chemical
Definition
-
Cell-surface proteins that bind gamma-aminobutyric acid with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
Source: Medical Subject Headings 2016
Type: Concept definition
Broader concept
Synonyms
- GABA receptors
In other languages
URI
https://lod.nal.usda.gov/nalt/271233
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