Concept information
- Research, Technology, Methods
- amino acids, peptides and proteins
- peptides
- cytokines
- colony-stimulating factors
Preferred term
macrophage colony-stimulating factor
Type
-
Chemical
Definition
-
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (macrophage colony-stimulating factor receptor).
Source: Medical Subject Headings 2015
Type: Concept definition
Broader concept
Synonyms
- colony stimulating factor 1
- colony stimulating factor-1
In other languages
URI
https://lod.nal.usda.gov/nalt/28007
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