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Concept information

Preferred term

macrophage colony-stimulating factor

Type

  • Chemical

Definition

  • Information A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (macrophage colony-stimulating factor receptor).

Synonyms

  • colony stimulating factor 1
  • colony stimulating factor-1

URI

https://lod.nal.usda.gov/nalt/28007

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RDF/XML TURTLE JSON-LD Created 1/19/06, last modified 5/20/16