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Concept information

Preferred term

focal adhesions

Type

  • Topic

Definition

  • Information An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the actin cytoskeleton terminate and attach to the transmembrane linkers, integrins, which in turn attach through their extracellular domains to extracellular matrix proteins.

Broader concept

Synonyms

  • cell-matrix adherens junctions
  • focal contacts

In other languages

URI

https://lod.nal.usda.gov/nalt/294139

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