Concept information
Preferred term
focal adhesions
Type
-
Topic
Definition
-
An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the actin cytoskeleton terminate and attach to the transmembrane linkers, integrins, which in turn attach through their extracellular domains to extracellular matrix proteins.
Source: Medical Subject Headings 2017
Type: Concept definition
Broader concept
Synonyms
- cell-matrix adherens junctions
- focal contacts
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/294139
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