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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. biochemical compounds
  3. growth factors
  4. endothelial growth factors
  5. vascular endothelial growth factors
  6. placental growth factor
  1. Research, Technology, Methods
  2. biochemical compounds
  3. growth factors
  4. endothelial growth factors
  5. vascular endothelial growth factors
  6. placental growth factor
  1. Fields of Study
  2. amino acids, peptides and proteins
  3. proteins
  4. animal proteins
  5. pregnancy proteins
  6. placental growth factor
  1. Research, Technology, Methods
  2. amino acids, peptides and proteins
  3. proteins
  4. animal proteins
  5. pregnancy proteins
  6. placental growth factor

Preferred term

placental growth factor

Type

  • Chemical

Definition

  • Information An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.

    Source: Medical Subject Headings 2017

    Type: Concept definition

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URI

https://lod.nal.usda.gov/nalt/308277

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RDF/XML TURTLE JSON-LD Created 9/12/17, last modified 11/22/17