Concept information
Preferred term
fibrillins
Type
-
Chemical
Definition
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A family of extracellular matrix glycoproteins that is structurally similar to latent TGF-beta binding proteins, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm microfibrils that function in a variety of cell interactions with the extracellular matrix and developmental processes such as elastic tissue maintenance and assembly, and the targeting of growth factors to the extracellular matrix.
Broader concept
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/317258
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