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Concept information

Preferred term

fibrillins

Type

  • Chemical

Definition

  • Information A family of extracellular matrix glycoproteins that is structurally similar to latent TGF-beta binding proteins, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm microfibrils that function in a variety of cell interactions with the extracellular matrix and developmental processes such as elastic tissue maintenance and assembly, and the targeting of growth factors to the extracellular matrix.

In other languages

URI

https://lod.nal.usda.gov/nalt/317258

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RDF/XML TURTLE JSON-LD Created 5/25/18, last modified 11/14/18