Concept information
Preferred term
fibrillins
Type
-
Chemical
Definition
-
A family of extracellular matrix glycoproteins that is structurally similar to latent TGF-beta binding proteins, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm microfibrils that function in a variety of cell interactions with the extracellular matrix and developmental processes such as elastic tissue maintenance and assembly, and the targeting of growth factors to the extracellular matrix.
Source: Medical Subject Headings 2018
Type: Concept definition
Broader concept
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/317258
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