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Concept information

Preferred term

methimazole

Type

  • Chemical

Definition

  • Information A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.

Broader concept

Synonyms

  • 1-methyl-2-mercaptoimidazole
  • tapazole

In other languages

URI

https://lod.nal.usda.gov/nalt/329505

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