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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. toxic substances
  3. toxins
  4. microbial toxins
  5. bacterial toxins
  6. diphtheria toxin
  1. Animals, Livestock, One Health
  2. toxic substances
  3. toxins
  4. microbial toxins
  5. bacterial toxins
  6. diphtheria toxin
  1. Fields of Study
  2. toxic substances
  3. toxins
  4. microbial toxins
  5. bacterial toxins
  6. diphtheria toxin
  1. Animals, Livestock, One Health
  2. toxic substances
  3. toxins
  4. microbial toxins
  5. bacterial toxins
  6. diphtheria toxin
  1. Research, Technology, Methods
  2. toxic substances
  3. toxins
  4. microbial toxins
  5. bacterial toxins
  6. diphtheria toxin

Preferred term

diphtheria toxin

Type

  • Chemical

Definition

  • Information An ADP-ribosylating polypeptide produced by Corynebacterium diphtheriae that causes the signs and symptoms of diphtheria. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains mono(ADP-ribose) transferases which transfers ADP ribose to peptide elongation factor 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.

    Source: Medical Subject Headings

    Type: Concept definition

Broader concept

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In other languages

URI

https://lod.nal.usda.gov/nalt/332175

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RDF/XML TURTLE JSON-LD Created 7/10/19, last modified 11/25/19