Concept information
Preferred term
aldo-keto reductases
Type
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Chemical
Definition
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A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, ketosteroids; keto-prostaglandins, and quinones. they are monomers of approximately 37 kda and are characterized by a parallel beta-8 (beta sheet)-alpha 8 (alpha helices)-barrel structure that contains the nadp binding site. This conformation favors aromatic and apolar substrates.
Source: Medical Subject Headings
Type: Concept definition
Broader concept
Narrower concepts
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/341300
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