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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Fields of Study
  2. genetics
  3. molecular genetics
  4. gene expression regulation
  5. gene silencing
  6. RNA interference

Preferred term

RNA interference

Type

  • Topic

Definition

  • Information A gene silencing phenomenon whereby specific dsRNAs (RNA, double-stranded) trigger the degradation of homologous mRNA (RNA, messenger). The specific dsRNAs are processed into small interfering RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-induced silencing complex. DNA methylation may also be triggered during this process.

    Source: Medical Subject Headings 2015

    Type: Concept definition

Broader concept

Related concepts

Synonyms

  • post-transcriptional gene silencing
  • posttranscriptional gene silencing
  • RNA interference (RNAi)
  • RNAi (RNA interference)
  • RNA silencing

In other languages

URI

https://lod.nal.usda.gov/nalt/42581

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RDF/XML TURTLE JSON-LD Created 1/19/06, last modified 3/22/16