Concept information
Preferred term
rifampicin
Type
-
Chemical
Definition
-
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms.
Source: Medical Subject Headings 2011
Type: Concept definition
Broader concept
Synonyms
- rifadin
- rifampin
- rimactan
In other languages
-
Spanish
URI
https://lod.nal.usda.gov/nalt/61571
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