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Concept information

Preferred term

buprenorphine

Type

  • Chemical

Definition

  • Information A derivative of the opioid alkaloid thebaine that is a more potent and longer lasting analgesic than morphine. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.

Synonyms

  • buprenorphine hydrochloride

In other languages

URI

https://lod.nal.usda.gov/nalt/8452

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RDF/XML TURTLE JSON-LD Created 1/19/06, last modified 6/30/16