Concept information
- Fields of Study
- phosphotransferases (kinases)
- protein kinases
- protein-tyrosine kinases
- receptor protein-tyrosine kinase
Término preferido
insulin receptors
Tipo
-
Chemical
Definición
-
A cell surface receptor for insulin. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic tyrosine kinase domain that is located within the beta subunit. Activation of the receptor by insulin results in numerous metabolic changes including increased uptake of glucose into the liver, muscle, and adipose tissue.
Fuente: Medical Subject Headings 2014
Tipo: Concept definition
Concepto genérico
Conceptos específicos
Sinónimos
- insulin-dependent tyrosine protein kinase
- insulin receptor alpha chain
- insulin receptor alpha subunit
- insulin receptor beta chain
- insulin receptor beta subunit
- insulin receptor protein-tyrosine kinase
En otras lenguas
-
español
URI
https://lod.nal.usda.gov/nalt/222855
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