Skip to main
An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Research, Technology, Methods
  2. drugs
  3. antineoplastic agents
  4. etoposide
  1. Research, Technology, Methods
  2. aromatic compounds
  3. phenolic compounds
  4. lignans
  5. podophyllotoxin
  6. etoposide
  1. Research, Technology, Methods
  2. polycyclic aromatic hydrocarbons
  3. naphthalenes
  4. tetrahydronaphthalenes
  5. podophyllotoxin
  6. etoposide
  1. Research, Technology, Methods
  2. polycyclic aromatic hydrocarbons
  3. naphthalenes
  4. tetrahydronaphthalenes
  5. podophyllotoxin
  6. etoposide
  1. Research, Technology, Methods
  2. polycyclic aromatic hydrocarbons
  3. naphthalenes
  4. tetrahydronaphthalenes
  5. podophyllotoxin
  6. etoposide

Término preferido

etoposide

Tipo

  • Chemical

Definición

  • Information A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.

    Fuente: Medical Subject Headings 2015

    Tipo: Concept definition

Concepto genérico

Conceptos relacionados

En otras lenguas

URI

https://lod.nal.usda.gov/nalt/262750

Descargue este concepto:

RDF/XML TURTLE JSON-LD Creado 7/10/15, última modificación 10/2/16