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NALT Full

Término preferido

up-and-down procedure (UDP)

Definición

This test is an alternative to the Median Lethal Dose (LD50) test in which animals are used for acute toxicity testing. Animals are dosed one at a time with a drug or toxic substance. If an animal survives, the dose for the next animal is increased; if it dies, the dose is decreased to determine toxicity level.
Fuente: Based upon Bruce R. D. (1985). An up-and-down procedure for acute toxicity testing. Fundamental and applied toxicology : official journal of the Society of Toxicology, 5(1), 151–157.
Tipo: Concept definition

Concepto genérico

computational toxicology

En otras lenguas

procedimiento de subida y bajada (UDP)

español

URI

https://lod.nal.usda.gov/nalt/28890315

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