Concept information
- Fields of Study
- biochemical compounds
- growth factors
- endothelial growth factors
- vascular endothelial growth factors
Término preferido
placental growth factor
Tipo
-
Chemical
Definición
-
An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.
Fuente: Medical Subject Headings 2017
Tipo: Concept definition
Concepto genérico
En otras lenguas
URI
https://lod.nal.usda.gov/nalt/308277
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}