Concept information
Término preferido
diphtheria toxin
Tipo
-
Chemical
Definición
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An ADP-ribosylating polypeptide produced by Corynebacterium diphtheriae that causes the signs and symptoms of diphtheria. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains mono(ADP-ribose) transferases which transfers ADP ribose to peptide elongation factor 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.
Fuente: Medical Subject Headings
Tipo: Concept definition
Concepto genérico
En otras lenguas
-
español
URI
https://lod.nal.usda.gov/nalt/332175
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