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NALT Concept Space
U.S. Department of Agriculture

NALT Full

Concept information

  1. Research, Technology, Methods
  2. drugs
  3. anti-infective agents
  4. antibiotics
  5. peptide antibiotics
  6. actinomycin D
  1. Fields of Study
  2. biochemical compounds
  3. amino acids, peptides and proteins
  4. peptides
  5. cyclic peptides
  6. actinomycin D
  1. Research, Technology, Methods
  2. biochemical compounds
  3. amino acids, peptides and proteins
  4. peptides
  5. cyclic peptides
  6. actinomycin D
  1. Research, Technology, Methods
  2. chemical substances
  3. chemical compounds
  4. organic compounds
  5. heterocyclic compounds
  6. actinomycin D
  1. Research, Technology, Methods
  2. drugs
  3. antineoplastic agents
  4. actinomycin D

Término preferido

actinomycin D

Tipo

  • Chemical

Definición

  • Information A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from Streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy.

    Fuente: Medical Subject Headings 2011

    Tipo: Concept definition

Concepto genérico

Sinónimos

  • dactinomycin

En otras lenguas

URI

https://lod.nal.usda.gov/nalt/3814

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