Concept information
Término preferido
prions
Tipo
-
Chemical
Definición
-
Small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc; the cellular isoform is PrPC. The primary amino acid sequence of the two isoforms is identical. Among diseases caused by prions are scrapie, bovine spongiform encephalopathy, and Creuzfeldt-Jakob Syndrome.
Fuente: Medical Subject Headings
Tipo: Concept definition
Concepto genérico
Conceptos específicos
Sinónimos
- prion proteins
- PrP proteins
En otras lenguas
-
español
URI
https://lod.nal.usda.gov/nalt/40965
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}