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Concept information

Término preferido

prions

Tipo

  • Chemical

Definición

  • Information Small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc; the cellular isoform is PrPC. The primary amino acid sequence of the two isoforms is identical. Among diseases caused by prions are scrapie, bovine spongiform encephalopathy, and Creuzfeldt-Jakob Syndrome.

Concepto genérico

Conceptos específicos

Sinónimos

  • prion proteins
  • PrP proteins

En otras lenguas

URI

https://lod.nal.usda.gov/nalt/40965

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RDF/XML TURTLE JSON-LD Creado 19/1/06, última modificación 30/12/15